Two years following his cancer diagnosis, Ben Stiller broke his silence on the matter during a 2016 appearance on The Howard Stern Show in an effort to promote the PSA test for prostate cancer screening. Calling it "a very controversial subject," Stiller explained, "The PSA test is the only early screener for prostate cancer and, right now, the United States Preventative Services Task Force does not recommend to take the test." The actor-director added, "I think American Cancer Society says you should discuss it at 50. If I hadn't taken the test — my doctor started giving it to me at 46 — I would not have known. Right now, I still wouldn't have known."
Around that time, Stiller further discussed the test and his "mid-range aggressive cancer," which was found in a tumor, in a piece penned for Medium. "Surgery was recommended," he wrote. "Ultimately, I found a wonderful surgeon named Edward Schaeffer who I felt comfortable with. He performed a robotic assisted laparoscopic radical prostatectomy." The operation was thankfully a success, with Stiller adding, "As of this writing I am two years cancer free and extremely grateful."