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Tabriz was chosen as the capital by several rulers commencing from the time of Atropates. It was the capital of the Ilkhanate (Mongol) dynasty since 1265. During the Ghazan Khan era, who came into power in 1295, the city reached its highest splendor. The later realm stretched from the Amu Darya in the East to the Egypt borders in the West and from the Caucasus in the North to the Indian Ocean in the South. It was again the capital of Iran during the Qara Qoyunlu dynasty from 1375 to 1468 and then during the Ag Qoyunlu within 1468–1501. Finally, it was the capital of the Iranian Empire in the Safavid period from 1501 until their defeat in 1555.
During the Qajar dynasty, Tabriz was used as the residence center of Iranian Crown Prince (1794–1925).