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In 2013 Oscar winner Jolie told the world that she had made the decision because she had a high risk of developing breast cancer. The reason Jolie was at increased risk was because she had what’s called a BRCA1 gene mutation. Doctors estimated she had an 87 percent chance of developing the disease. She also had a 50 percent risk of ovarian cancer, which is linked to the BRCA1 gene mutation as well.